Original Word: ἀντικαθίστημι
Part of Speech: Verb
Transliteration: antikathistémi
Pronunciation: an-tee-kath-is'-tay-mee
Phonetic Spelling: (an-tee-kath-is'-tay-mee)
KJV: resist
NASB: resisted
Word Origin: [from G473 (ἀντί - instead) and G2525 (καθίστημι - made)]

1. to set down (troops) against, i.e. withstand

resist.

From anti and kathistemi; to set down (troops) against, i.e. Withstand -- resist.

see GREEK anti

see GREEK kathistemi

Word Origin
from anti and kathistémi
Definition
to set down against, i.e. to replace, oppose
NASB Translation
resisted (1).

STRONGS NT 478: ἀντικαθίστημι

ἀντικαθίστημι: 2 aorist ἀντικατεστην; (from Herodotus down); in the transitive tenses:

1. to put in place of another.

2. to place in opposition (to dispose troops, set an army in line of battle); in the intransitive tenses, to stand against, resist: Hebrews 12:4, (Thucydides 1, 62. 71).

Topical Overview

The single New Testament appearance of this verb (Hebrews 12:4) depicts an active, forceful resistance in the face of hostility. It evokes the imagery of a combatant who plants his feet and pushes back until victory is secured, even at great personal cost.

Immediate Context in Hebrews 12

Hebrews 11 has just paraded generations of faithful witnesses who endured torture, chains, and death (Hebrews 11:35-38). Chapter 12 then urges believers to “run with endurance” (Hebrews 12:1), fixing their eyes on Jesus, who “endured the cross” (Hebrews 12:2). Against that backdrop the writer states, “In your struggle against sin, you have not yet resisted to the point of shedding your blood” (Hebrews 12:4). The word underscores a contrast: the recipients’ present hardships are real yet not as extreme as those of prior saints or of Christ Himself.

Old Testament Roots and Patterns

Although this particular Greek term is unique to Hebrews, the call to steadfast resistance permeates the Old Testament narrative. Joseph resisted the sexual advances of Potiphar’s wife at the risk of imprisonment (Genesis 39:7-12). Elijah confronted idolatrous prophets on Mount Carmel (1 Kings 18:20-40). Daniel and his friends defied imperial decrees that violated loyalty to the covenant God (Daniel 3:16-18; Daniel 6:10). Such examples illustrate the continuity of God’s expectation that His people resist sin and remain loyal regardless of opposition.

Christological Fulfillment

Jesus is the supreme embodiment of this resistance. He withstood every temptation (Matthew 4:1-11), faced contradiction from sinners (Hebrews 12:3), and shed His blood on the cross. By highlighting believers’ lesser sufferings, Hebrews 12:4 points to Christ’s greater sacrifice, urging them to draw strength from His victorious endurance.

Theological Significance

1. Perseverance: The verb portrays sanctification not as passive refinement but as active warfare. Believers are enlisted to fight until sin is mortified (Romans 8:13).
2. Discipline: The following verses link resistance to the Father’s loving discipline (Hebrews 12:5-11). Opposition is not a sign of abandonment but of filial training.
3. Spiritual Warfare: While Hebrews 12:4 focuses on resisting sin, other passages apply similar language to demonic opposition (James 4:7; 1 Peter 5:9). Together they depict a holistic battle against evil in its internal and external forms.

Historical Reception

Early Christian writers applied Hebrews 12:4 to martyrdom. Ignatius of Antioch encouraged believers to “imitate the passion of my God,” anticipating his own bloodshed. During later persecutions, countless martyrs interpreted their sufferings as the fulfillment of this verse. The Reformers likewise cited it to fortify congregations facing state and ecclesiastical pressures.

Practical Ministry Applications

• Pastoral Encouragement: When counseling persecuted or tempted believers, Hebrews 12:4 offers both honesty (“struggle”) and hope (“not yet to blood”).
• Discipleship: Spiritual disciplines—Scripture meditation, prayer, corporate worship—are means by which resistance is strengthened (Ephesians 6:10-18).
• Ethics: The verse demolishes complacency. Sin is not a nuisance to be tolerated but an enemy to be opposed decisively.
• Missions: Believers serving in hostile contexts find in this text a mandate to endure, assured that faithful resistance has always marked gospel advance.

Related Biblical Exhortations

James 4:7: “Submit yourselves therefore to God. Resist the devil, and he will flee from you.”

1 Peter 5:9: “Resist him, standing firm in your faith, because you know that your brothers throughout the world are undergoing the same kinds of suffering.”

2 Timothy 2:3: “Share in suffering as a good soldier of Christ Jesus.”

Conclusion

The lone occurrence of Strong’s Greek 478 crystallizes the believer’s calling to unwavering opposition against sin and all its agents. Anchored in Christ’s own blood-shedding resistance and surrounded by a cloud of historical witnesses, the church is exhorted to stand firm—whatever the cost—until the final victory promised by God is fully realized.

αντικαταστήσεται αντικατέστησεν αντικατεστητε αντικατέστητε ἀντικατέστητε antikatestete antikatestēte antikatéstete antikatéstēteInterlinear Greek • Interlinear Hebrew • Strong's Numbers • Englishman's Greek Concordance • Englishman's Hebrew Concordance • Parallel Texts