The term marked by Strong’s 5105 functions as an emphatic inferential conjunction. It gathers what has just been argued and presses the reader to embrace the inevitable conclusion. Unlike the simpler “therefore” (διό, οὖν), the form carries an added rhetorical force: “this being so, then…”.

Biblical Usage

1 Thessalonians 4:8 and Hebrews 12:1 preserve the only New Testament appearances. Both letters are pastoral in tone yet weighty in doctrine, and each writer employs the term to bind foundational theology to urgent exhortation.

• 1 Thessalonians 4:8 sets holiness in moral conduct on the same plane as reverence for God Himself: “Therefore, whoever rejects this instruction does not reject man, but God, who gives you His Holy Spirit”. Paul moves seamlessly from a call to sexual sanctity (4:3–7) to the sober warning that refusal equals divine rejection.
• Hebrews 12:1 pivots from the catalog of faith in Hebrews 11 to a call for persevering discipleship: “Therefore, since we are surrounded by such a great cloud of witnesses, let us throw off every encumbrance…”. The exhortation to endurance is built upon the testimony of those who lived by faith.

Theological Implications

1. Authority of Divine Mandate. In Thessalonica the conjunction strengthens the link between apostolic command and God’s own authority, making obedience a matter of covenant loyalty rather than mere counsel.
2. Continuity of Redemptive History. Hebrews deploys the word to show that the Old Testament saints’ faith is not a museum piece but the ground on which New Covenant believers are to run. The conjunction secures the unity of Scripture’s witness.
3. Sanctification as Response. Both texts demonstrate that sanctified living is the logical outcome of received grace. Doctrine drives duty; indicatives birth imperatives.

Historical Context in Greek Rhetoric

Classical and Hellenistic orators used the expression to intensify closing arguments. By adopting this heightened connector, the biblical authors speak in a register familiar to the educated Greco-Roman ear, lending solemnity and persuasion to their appeals. This echoes the Spirit’s intent to reach every linguistic stratum without diluting truth.

Practical Ministry Applications

• Counseling: When urging believers toward purity or perseverance, ground appeals in the finished work of Christ and the indwelling Spirit, then press the “therefore.”
• Discipleship: Map study materials so that doctrinal sessions (e.g., identity in Christ) are immediately followed by sessions on conduct, mirroring the logic of the two passages.
• Corporate Worship: Read Hebrews 11 followed by 12:1–3 to frame the congregation’s call to steadfastness within the legacy of faith.

Homiletical Insights

A sermon built around 5105 should highlight three movements: (1) Review the preceding truth, (2) Announce the consequential “therefore,” (3) Call for specific obedience. Emphasize that gospel logic never leaves hearers neutral—grace demands response.

Summary

Strong’s 5105 seals argument to application with emphatic finality. In Paul it warns that rejecting holiness equals rejecting God; in Hebrews it rallies the saints to finish their race by the power of witnessed faith. The word embodies the Bible’s own pattern: revelation received, response required.