642. aporphanizó
Lexical Summary
aporphanizó: To be bereaved, to be orphaned, to be left without

Original Word: ἀπορφανίζω
Part of Speech: Verb
Transliteration: aporphanizó
Pronunciation: ah-por-fan-ID-zo
Phonetic Spelling: (ap-or-fan-id'-zo)
KJV: take
NASB: taken away
Word Origin: [from G575 (ἀπό - since) and a derivative of G3737 (ὀρφανός - orphans)]

1. to bereave wholly
2. (figuratively) separate (from intercourse)

Strong's Exhaustive Concordance
to make an orphan of

From apo and a derivative of orphanos; to bereave wholly, i.e. (figuratively) separate (from intercourse) -- take.

see GREEK apo

see GREEK orphanos

HELPS Word-studies

642 aporphanízō (from 575 /apó, "separate from" and 3737 /orphanós, "leave as an orphan") – properly, to orphan; (figuratively) deprive, leaving someone defenseless – like an orphan, bereft of a father's care and instruction (used only in 1 Thes 2:17).

NAS Exhaustive Concordance
Word Origin
from apo and orphanizó (to make orphan, destitute)
Definition
to be bereaved
NASB Translation
taken away (1).

Thayer's Greek Lexicon
STRONGS NT 642: ἀπορφανίζω

ἀπορφανίζω: (1 aorist passive participle ἀπορφανισθεις); (from ὀρφανός bereft, and ἀπό namely, τίνος), to bereave of a parent or parents (so Aeschylus choiëph. 247 (249)); hence, metaphorically, ἀπορφανισθέντες ἀφ' ὑμῶν bereft of your contact and society, 1 Thessalonians 2:17 (here Rec.elz (by mistake) ἀποφανισθεντες.

Topical Lexicon
Scope and Nuance of the Word

Ἀπορφανίζω depicts an abrupt and painful severing of relationship, conveying the sense of being “orphaned” or “bereft.” While its only New Testament occurrence concerns apostolic separation rather than literal parent-child loss, the term carries the weight of parental tenderness suddenly interrupted.

Biblical Occurrence and Context

1 Thessalonians 2:17: “But brothers, when we were separated from you for a short time—in person but not in heart—we were all the more eager, with great desire, to see you face to face”. Paul recalls the forced departure from Thessalonica (Acts 17:1-10). He and his team had nurtured the fledgling church “like a nursing mother” (1 Thessalonians 2:7) and “like a father” (2:11). The verb ἀπορφανισθέντες crystallizes how unnatural that rupture felt: spiritual parents torn from their children.

Historical Background

Thessalonica lay on the Via Egnatia, a strategic Roman route. Jewish opposition and city unrest compelled Paul’s night escape, leaving converts exposed to persecution. The sense of sudden orphanhood is historical as well as emotional; the local believers lost their primary teachers within weeks of conversion. This explains Paul’s urgency in dispatching Timothy (1 Thessalonians 3:2) and his second-letter reassurance (2 Thessalonians 2:15) that oral and written instruction stand together.

Theological Themes and Ministry Implications

1. Spiritual Parenthood: Genuine gospel ministry births responsibility akin to fatherhood and motherhood. Separation from those discipled should never be casual; Paul’s grief models shepherd-like commitment (cf. John 10:12-13).
2. The Church as Family: The orphan metaphor reminds believers that new converts are not clients but children of God placed in household fellowship (Ephesians 2:19).
3. Longing for Presence: Though epistles carry apostolic authority, they never replace embodied fellowship. Paul’s passionate desire “to see you face to face” legitimizes current longings for corporate gathering (Hebrews 10:24-25).
4. Assurance amid Absence: Even when human mentors are absent, Christ promises, “I will not leave you as orphans” (John 14:18). The Spirit sustains growth until reunions occur—whether earthly or in glory.

Related Scriptural Imagery

• God the “Father of the fatherless” (Psalm 68:5) underscores His protective character whenever orphan language appears.
James 1:27 commends pure religion that visits “orphans and widows in their distress,” broadening physical care to all who feel abandoned.
• Paul’s similar ache for Corinth—“I do not write these things to shame you, but as my beloved children I warn you” (1 Corinthians 4:14)—shows the orphan motif echoed by paternal concern elsewhere.

Practical Application for Believers

• Evaluate discipleship through the lens of family responsibility, not transactional engagement.
• Recognize the pain caused when shepherds are removed; pray for persecuted congregations suddenly leaderless.
• Pursue intentional presence: letters, calls, and visits restore unity when distance occurs.
• Anchor hope in God’s promise that no believer is ever truly orphaned; the Spirit secures continual guidance.

Summary

Strong’s Greek 642 captures the intense sorrow of forced separation between spiritual parents and children. Rooted in Paul’s Thessalonian experience, it urges every generation of believers to cherish fellowship, guard the vulnerable, and trust the faithful Father who never abandons His own.

Forms and Transliterations
απέσαξε απεσιώπησαν απορφανισθεντες απορφανισθέντες ἀπορφανισθέντες αποσβέννυται αποσβεσθήσεται αποσειόμενος aporphanisthentes aporphanisthéntes
Links
Interlinear GreekInterlinear HebrewStrong's NumbersEnglishman's Greek ConcordanceEnglishman's Hebrew ConcordanceParallel Texts
Englishman's Concordance
1 Thessalonians 2:17 V-APP-NMP
GRK: δέ ἀδελφοί ἀπορφανισθέντες ἀφ' ὑμῶν
NAS: But we, brethren, having been taken away from you for a short
KJV: we, brethren, being taken from you
INT: moreover brothers having been bereaved of you

Strong's Greek 642
1 Occurrence


ἀπορφανισθέντες — 1 Occ.

641
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